One of the highest priorities for Spectrum Protect (TSM) development is enhancing the integration between Microsoft Applications like SQL Server and Exchange and Spectrum Protect when they are hosted in a VMware Environment.
Version 7.1.2 of Spectrum Protect for Mail enhances Microsoft Exchange integration when the Exchange servers are hosted in VMware and the virtual Machines are backed Up with Spectrum Protect for Virtual Environments.
In this short video, I show the new combined GUI that allows you to do a Exchange 2013 database restore directly from a backed up VM .
The development team for Protect has written a very good white paper that discusses the many options for using Protect in virtualized environments. It's highly reccomended if your backing up an application that is virtualized.